PhenoPath at USCAP 2006 Annual Meeting

PhenoPath Laboratories was an active participant in the 2006 Annual Meeting of the United States and Canadian Academy of Pathology in Atlanta, Georgia from February 11 – 17, 2006. Our pathologists presented several abstracts highlighting our ongoing clinical research studies. PhenoPath also exhibited at the meeting from Feb. 13-15, showcasing new immunohistochemistry and molecular tests, along with our new 9-color flow cytometry service.

Special Evening Presentation

Dr. Allen M. Gown of PhenoPath Laboratories presented a talk entitled, "Are we erring in the ER testing of breast cancer by IHC?" during a special evening presentation cosponsored by Lab Vision - NeoMarkers and PhenoPath. Dr. Gown was joined by Dr. Paolo Dei Tos, from Treviso, Italy to share details from his recently published paper entitled, "A comparative study between a novel category of immunoreagents and the corresponding mouse monoclonal antibodies." The presentation was on Monday, February 13, 2006 from 5:30 to 7:30 pm in the Kennesaw Room at the Hyatt Regency Hotel, Atlanta. Dr. Gown's presentation is available for download.

Short Course Presentation

Dr. Todd S. Barry of PhenoPath Laboratories, along with Dr. Neal Goldstein of William Beaumont Hospital, Michigan, teamed up to present a brand new short course entitled, Update and Troubleshooting Immunohistochemistry for Pathologists on Thursday, February 16 from 1:00 to 4:30 PM in the Regency VII room at the Hyatt Regency Hotel, Atlanta. This course included short lectures on creating antibody panels for, and interpreting immunostains performed on, small needle core biopsies. Topics also included: the advantages and disadvantages of specific commercial antibodies; troubleshooting guidelines for pathologists; the most common causes and solutions to suboptimal automated instrument immunostains. This course was designed for the practicing and in-training anatomic pathologist.

USCAP Presentations by PhenoPath Pathologists

Sunday, February 12, 2006:

A.M. Gown presented, "FISH Testing for HER2 Detection." This 20-minute talk was held during an evening program entitled, "HER2 Assessment: Better Testing for Better Outcomes," sponsored by Albert Einstein College of Medicine and Montefiore Medical Center and M2 Communications. This program is supported by an unrestricted educational grant from Genentech, Inc. The 2-hour program starts at 5:30 pm in the Manila Room at the Hyatt Regency Hotel.

Monday, February 13, 2006:

Poster #200, Morning Session
D.N. Ionescu, D. Treaba, C.B. Gilks, J. Laskin, R. Wood-Baker, A.M. Gown: Tissue Microarray and Immunohistochemical Analysis of Neuroendocrine Differentiation in Non-Small Cell Lung Carcinoma (NSCC).

Platform Presentation, Section C, 11 AM
R. Vang, A.M. Gown, T.S. Barry, D.T. Wheeler, K. Judson, B.M. Ronnett: P16 Expression in Primary Ovarian Mucinous and Endometrioid Tumors and Metastatic Adenocarcinomas in the Ovary: Utility for Identification of Metastatic HPV-Related Endocervical Adenocarcinomas.

Platform Presentation, Section C, 11:15 AM
D.N. Ionescu, H. Masoudi, S. Leung, A.M. Gown, C.B. Gilks: Expression of Mesothelial Markers in Ovarian Cancers: A Tissue Microarray Based Study of 471 Cases.

Platform Presentation, Section H, 2:45 PM
R.R. Tubbs, J.D. Pettay, M.B. Hartke, T. Barry, G. Payne, P.C. Roche, M. Loftus, E. Swain, T.M. Grogan: Specificity of Interphase FISH Probes for Detection of Sarcoma and Lymphoma Associated Translocations in Paraffin Sections is Readily Assessed Using Tissue Microarrays Constructed from Murine Xenografts.

Tuesday, February 14, 2006:

Poster #104, Morning Session
P.L. Kandalaft, T.S. Barry, S.J. Kussick, L.C. Goldstein, C. Bacchi, P. Bitterman, A.M. Gown: Immunohistochemical Detection of Aquaporin 1 as an Aid in Identifying Renal Cell Carcinoma in the Setting of Metastatic Carcinomas of Unknown Primary.

Poster #143, Morning Session
D. Cimbaluk, J. Scudiere, J. Rotmensch, A.M. Gown, P. Bitterman: Uterine Carcinosarcoma: Immunohistochemical Studies on Tissue Microarrays with Focus on Potential Therapeutic Targets.

Poster #124, Afternoon Session
R. Vang, A.M. Gown, C. Zhao, T.S. Barry, B.M. Ronnett: Expression of CK7 and CK20 in Ovarian Mucinous Tumors Arising in Association with Teratomas: A CK7-/CK20+ Subset can Cause Confusion with Metastatic Lower Gastrointestinal (GI) Tract Mucinous Tumors.

Poster #129, Afternoon Session
M.A. Farinola, A.M. Gown, T.S. Barry, S. Movahedi-Lankarani, R. Vang: Comparative Immunohistochemical Analysis of ER/PR Expression in Ovarian Sertoli Cell Tumors (SCT) and Adult Granulosa Cell Tumors (AGCT).

Wednesday, February 15, 2006:

Poster #44, Afternoon Session
C.H. Tse, T.S. Barry, H. Hwang, D.O. Treaba, A.M. Gown: Improved Detection of Breast Carcinoma Using Mammaglobin and Gross Cystic Disease Fluid Protein-15 (GCDFP-15) by Immunohistochemistry.

Poster #210, Afternoon Session
S.J. Kussick, D. Ceniza, B.K. Oppenlander, T.S. Barry, A.M. Gown: Nine-Color/Eleven-Parameter Flow Cytometry can be Utilized in the Clinical Laboratory to Diagnose a Broad Range of Hematolymphoid Neoplasms.

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